Keto Longevity

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The idea of extended fasting is daunting to a lot of people – how on earth do you just not eat?!, however it might not be that you have to completely do without food in order to reap the benefits of fasting. Valter Longo’s Longevity diet is a perfect example of this – his regime of low calories, low protein for five days is suggested to confer the same benefits as fasting.

The overabundance of calories is undoubtedly a contributor to oxidative stress and damage that leads to cellular damage, so times of energy deprivation, well below usual daily intake, may well protect us in the long term. Thomas Seyfried, among others, feels that a fasting regime of at least three days may be enough to clear out damaged cells, however for some people that might not be a realistic option for whatever reason. 

Rather than restricting all calories, a 50% caloric reduction in a time restricted eating window that was ketogenic this would

• suppress insulin
• suppress mTOR (and IGF-1; both stimulators of growth in the body)
• reduce ATP signaling to the cells (energy signaling)
• reduce blood glucose levels.
• Potentially upregulate autophagy